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Acute Post streptococcal Glomerulonephritis (APSGN) is an important renal disease occurring in children. Typical clinical manifestations include rapid onset of gross haematuria, edema and hypertension resulting from a prior group A - beta hemolytic streptococcal infection. However, patients with APSGN sometimes present with atypical clinical manifestations often leading to delayed diagnosis or misdiagnosis. Recognition of these unusual manifestations is important so that patient receives adequate treatment with decreased morbidity. We are reporting two cases of APSGN who presented with atypical manifestations. One case presented with generalized edema, respiratory distress and pulmonary edema with congestive heart failure and another with fever, headache, seizures and altered sensorium. Both patients had hypertension. Urinalysis and other investigations led to diagnosis of APSGN with pulmonary edema and heart failure in first case and APSGN with Posterior Reversible Encephalopathy syndrome in second.
Rosane Cavalcante Fragoso, Brasil
Chief Scientific Officer and Head of a Research Group
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