Comparison of efficacy of different diagnostic modalities of lung cancer: Bronchoscopic methods (BAL, TBNA, EBLB), ct-FNAC, pleural fluid (Aspiration cytology, Pleural biopsy), Lymph node FNAC

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Author: 
Kapil Sharma, Vishal Patidar, Avinash Jain, Sheena Taneja, Sudan, D. P. S., Monica Sharma and Mishra, J. K.
Subject Area: 
Health Sciences
Abstract: 

Background: Bronchogenic carcinoma usually has fatal consequences but early diagnosis remains a challenge in developing nation like India. Bronchoscopic methods and CT guided FNAC are valuable tools for early diagnosis of both central and peripheral lesions. Objectives: To compare the diagnostic efficacy of Bronchoscopic methods (BAL, TBNA), Pleural Fluid (aspiration cytology, pleural biopsy), Lymph node FNAC while considering CT-FNAC of lung masses and EBLB as Gold Standard tests. Materials and Methods: Study was carried out for more than 4 years and various modalities of lung cancer were offered for CT diagnosed cases of lung masses. Data of 198 cases was recorded for statistical analyses. Results: Study obtained higher sensitivity of BAL samples and Lymph node FNAC as 79.17% and 88.2 % respectively. However, there was low sensitivity of pleural fluid cytology and pleural biopsy as 26.4% and 11.11% respectively. The study recorded good specificity and accuracy for all the modalities. Conclusion: We conclude to perform CT guided FNAC of masses, Bronchoscopic methods and lymph node FNAC for early detection of bronchogenic carcinoma.

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Editorial Board Member's

Dr.Geetanjali Joshi Mishra
Lucknow, UP, INDIA
Dr. Sankalp Verma
India
Tannu Arora
India
Prof Dr. Lee Mun Seng
Malaysia
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
Dr. Lim Gee Nee
Malaysia
DANA MOHAMMED
UK
Ali Majnoony Tootakhaneh
Iran
Prof. Somchai Amornyotin
Thailand
Nurhodja Akbulaev
Turkey
Muhammad Hamid
Pakistan
MOHAMMAD GHOLAMI
Iran
MAVLYANOV ISKANDAR RAKHIMOVICH
Uzbekistan
Hasan Ali Abed Al-Zu’bi
Jordan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Eapen, Asha Sarah
USA
Dr. Ruchika Khanna
India
DR. MUHAMMAD ISMAIL MOHMAND
UK
DR. MAHESH SHIVAJI CHAVAN
India
Dr. Lokesh Gambhir
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
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India
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Indonesia
Bensafi Abd-El-Hamid
Algeria
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India
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India
Dr. Arun Kumar
India
DR. M. ARUNA
India
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Turkey
Yassine KADMI
French
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Dhaka
Jiban Shrestha
Nepal
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Tanzanian
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Egypt
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Iraq
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