Granisetron and ondansetron in prevention of post operative nausea Vomiting (ponv) in tonsillectomy

The most distressing symptoms that follow anaesthesia and surgery are pain and vomiting. The aim of this study is to compare the antiemetic efficacy of granisetron against that of ondansetron by comparing the incidence of PONV using each drug. The surgical technique is highly standardized, therefore the choice of anaesthetic technique is the main variable available to influence PONV. Patients who received Granisetron and Ondansetron had significantly less PONV compared to the group that received normal saline; and with Granisetron the incidence was significantly lower than that with Ondansetron.