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Table of Contents: Volume 18; Issue 03; March, 2026

Life Sciences

  1. Prakash, D.S.R.S. and Preethi Chandrakala, B.
    ABSTRACT:

    To isolate the Aflatoxin producing Aspergillus species in different infected food materials, ground nuts, maize and coconut endosperm are infected with different types of fungal species in which some are contaminated with aflatoxin producing aspergillus species. The aflatoxin production was observed the plates are exposed to UV light followed TLC method. Then the aflatoxin producing species are identified by their growth on coconut agar medium blue fluorescence was observed when exposed to a UV-light, Aflatoxins are highly toxic, carcinogenic compounds produced by certain fungi (Aspergillus flavus and A. parasiticus) that grow on crops, particularly in warm, humid conditions. They commonly contaminate ground nuts, maize, coconut, peanuts, corn, tree nuts, and spices, posing serious liver cancer risks to humans and animals.

  2. Ms. Vasantha, S. and Mrs. Renukadevi, D.N.
    ABSTRACT:

    Sleep hygiene is a group of behavioral and environmental practices that improves the quality of physical, mental and emotional well-being. Lifestyle factors such as increased screen time, work related stress, caffeine intake; environmental factors like noise and light can affect sleep hygiene. Poor sleep hygiene leads to physical, mental and cognitive health outcomes along with metabolic disorders, cardiovascular diseases and psychological disturbances. Sleep affects children, old age people, and healthcare workers in different ways. In children, academic workload, including online classes, e-learning, homework, and assignments, can leads to delay bedtime, and stress, anxiety reduces the quality sleep. Healthcare professionals working in shifts, particularly night shifts, experiences disturbed sleep, with 64–70% reporting poor sleep quality after completion of night shift. Old age people commonly face sleep problems such as insomnia and obstructive sleep apnea, due to medical comorbidities, Intake of medications such as diuretics, beta-blockers, antidepressant, and irregular daytime napping. These factors are effects on quality sleep and impacting physical and mental health. Sleep related problems are widely reported across the Indian population and it is a significant health issue in India, Studies indicates that approximately 25–30 % of Indian population is affected by insomnia, approximately 11 % of adults are affected by obstructive sleep apnea, with millions of people affected by moderate-to-severe forms of the disorder. In addition sleep disturbances are frequently reported among older adult and rural populations it indicating a considerable national burden this review highlights the concept of sleep hygiene, physiology of sleep, factors affecting for sleep hygiene, impacts of sleep hygiene on physical health, mental health, cognitive functioning and practices to promote healthy sleep hygiene.

  3. Dr. Tehzeeb Anis
    ABSTRACT:

    Background: Childbirth rituals are profoundly embedded in cultural traditions. These traditions cover a diverse array of beliefs, rituals, and societal conventions that influence the experiences and choices of women throughout pregnancy, labour, and delivery. Sacred rituals, folklore, and customs handed down through the ages all have an impact on culture. Objective: The aim of this study is to explore the traditional and cultural practices followed during pregnancy, childbirth and postpartum period. Methodology: Purposive sampling was used to choose the study participants. Data were gathered through comprehensive interviews. Thematic analysis was used to examine and understand the interview transcript and field notes. The researcher meticulously reviewed the transcript multiple times to enhance comprehension of the context and subsequently identified the principal themes and subthemes. Result: Respondents reported many cultural, traditional and religious practices experienced by the women of Deoria district during pregnancy, childbirth and postpartum period. Practices like restriction, tying black cloth around arm, wearing small knife, food taboos, burying of umbilical cord, confinement in a room after delivery, drinking holy water, praying to god and body massage were some of the practices followed by the women. Conclusion: Traditional and cultural practices significantly influence women's experiences of pregnancy, childbirth, and the postpartum period in the Deoria district. Numerous behaviours provide emotional and social support; nonetheless, it is crucial to comprehend them to ensure that maternal healthcare interventions are safe and culturally respectful.

  4. OUATTARA Amidou, KONAN Kouassi Urbain, HIEN Marie-Paule et Kouamé Konan Firmin
    ABSTRACT:

    Conteste: La tomate (lycopersicum esculentum mill) oest le legume le plus consommé au monde. Elle occcupe une place de choix dans le maraîchage en raison de son importance économique et alimentaire. Malheureusement, sa production en milieu urbain comme Abidjan, est confrontée à des problèmes fonciers dues à l’extension de la ville. Objectif: Afin de soutenir durablement la production de la tomate, une étude a été menée, dans la commune de Marcory, (Abidjan)) dont l’objectif est de proposer une alternative de production durable de la tomate dans un context de pression foncière en milieu urbain Methodes: L’étude a été mené dans un dispositive Split plot comportant douze traitements issus d’une combinaison de trois fréquences d’arrosage (matin (M), matin et soir (ME) et soir (E)) et quatre niveaux de fertilisation à l'urée (F0 = mg/L, F1 = 4,6 mg/L, F2 = 6,9 mg/L et F3 = 9,2 mg/L). L’étude à consisté à comparer le rendement de la variété de tomate Lindo cultivée en hors sol et plein sol. Résultats: Les résultats obtenus montrent que la culture hors sol de la tomate a enregistré une hausse substantielle du rendement. A fréquence d'arrosage identique, c’est la dose de fertisant F3, (9, 2 mg/L).qui a permis d’enregistrer les hauts rendements. On a note une difference significative au second cycle, avec 30 t/ha contre à 1 t/ha pour un arrosage le matin. Quant à l'arrosage matin et soir, les rendements montrent aussi une différence significative entre les deux cycles de culture, avec 42 t/ha (cycle 1) et 31 t/ha(cycle 2) pour la tomate cultivée en hors sol contre à 1 t/ha ‘cycle1)et 1,1 t/ha (cycle 2) pour celle cultivée sur sol.. Il en est de même pour l'arrosage du soir, avec 31 t/ha et 30 t/ha, contre 1,5 t/ha et 2 t/ha. En somme, la culture hors sol permet une embellie des rendements de la tomate et peut etre une alternative viable pour pallier au manque d'espace pour une production de la tomate en milieu urbain.

  5. Anurag Krishna, Amit K. Keshari, Ramesh Kr. Gupta, and Satya Prakash Singh
    ABSTRACT:

    Targeted protein degradation (TPD) represents a transformative therapeutic modality that exploits the intracellular ubiquitin-proteasome system (UPS) to selectively eliminate disease-causing proteins. Within the TPD landscape, two distinct mechanistic classes have emerged: Proteolysis-Targeting Chimeras (PROTACs), bifunctional heterodimeric molecules that bridge a protein of interest (POI) with an E3 ubiquitin ligase via a chemical linker; and molecular glues, typically monofunctional small molecules that stabilize neo-substrate recruitment on the surface of an E3 ligase through induced protein-protein interaction interfaces. While PROTACs offer unparalleled modularity and rational design accessibility, molecular glues, exemplified by the immunomodulatory drug (IMiD) class and next-generation cereblon E3 ligase modulators (CELMoDs), have accumulated the most robust clinical validation in the field, including multiple FDA and EMA approvals for hematological malignancies. This review provides a comprehensive and critical comparative analysis of both paradigms, covering mechanism of action at atomic resolution, structural basis of E3 ligase recruitment, pharmacological properties, resistance mechanisms, and clinical development status. This review position as a compelling and clinically superior paradigm for targeted protein degradation, while acknowledging the complementary strengths that both classes offer to the broader TPD therapeutic landscape.

  6. Dr. Urvi Ashani and Baby Organo
    ABSTRACT:

    Background: This study aimed to evaluate the efficacy and safety of BabyOrgano Baalprashan Swarnaprashan Drops in enhancing immunity, promoting growth and improving overall well-being in children aged 5–15 years. Objectives: A total of 30 children (15 males, 15 females) participated in this observational study. Participants were primarily from the 5–10 years age group (n=24), with a smaller cohort aged 11–15 years (n=6). Methods: Anthropometric measurements, immune markers, frequency of illness episodes, and clinical impressions were assessed over a 90-day period. Results: Anthropometric parameters showed with a 3.12% increase in body weight, 0.38% in height, and respective improvements in WAZ (31.22%) and HAZ (22.52%). Chest circumference and mid-upper arm circumference increased by 2.21% and 2.78%, respectively. Conclusions: Anthropometric parameters showed positive trends improvement in body weight, height, WAZ, HAZ, chest circumference & mid-upper arm circumference. Clinical Global Impression – Improvement (CGI-I) scores reflected significant improvements, improved stamina, and immunity. BabyOrgano Baalprashan Swarnaprashan reduced the burden of illness, enhanced immune function, and promoted overall well-being in children. These results support its use as a better and effective pediatric health supplement.

  7. Donafani Siaka KONE and Gnoleba Jean Baptiste Richmond MADOU
    ABSTRACT:

    Colonisation has deeply impacted African identity, as it led to the distortion of indigenous cultures, and practices. The legacy left during that period, known as colonial heritage, has fostered the issue of race. Thus, racism appears as a strategy used by the colonizer to subjugate the colonized. Ultimately, Coetzee’s characters in boyhood are victims of marginalisation in schools and at work. This article attempts, by the means of post-colonial theory and critical race theory, to examine colonial heritage and racism through ideological states apparatuses. It shows how colonisers have settled a system of rule that has shaped African identity and culture. Thereby, colonial heritage distorts and disgraces African’s identity and culture through a clear-cut distinction between blacks and whites in South Africa.

  8. Hanmant M. Kasralikar
    ABSTRACT:

    Cu-NP/Chave been effectively used as catalyst for the synthesis of novel chromeno [4,3-b] chromene derivatives. Herein, a novel and convenient protocol have been developed for the synthesis Chromeno-chromene derivatives via multicomponent one pot reaction. We describe a one-pot three-component synthesis of novel derivatives starting from substituted salicylaldehyde, 4-hydroxy coumarin and indole/ barbituric acid using Cu-NP/C as an efficient catalyst at ambient temperature condition in ethyl alcohol with good yield.

Physical Sciences and Engineering

  1. Lègba Nazaire Aïzoun
    ABSTRACT:

    Mosquito control programs are now threatened by the selection of mosquito populations resistant to the chemical insecticides. Thus, alternative vector control methods are necessary. The current study was aimed to study the effects of synergist piperonyl butoxide (PBO) on lambdacyhalothrin tolerance on Anopheles gambiae sensu lato larvae from Toviklin district in Couffo department in south-western Benin, West Africa. Larvae and pupae were collected from April to July 2024 during the great rainy season in Toviklin district. Larval bioassays were performed on these collected Anopheles gambiae s.l. larvae using lambdacyhalothrin as larvicide and piperonyl butoxide (PBO) as enzyme inhibitor or synergist. The results showed that mono-oxygenase enzymes played a role in Anopheles gambiae s.l. larvae tolerance to lambdacyhalothrin in Toviklin district. Synergist PBO contributes to improve the efficacy of insecticide when problems of resistance have arisen.

  2. Dr. Vimal, A.
    ABSTRACT:

    The correlation between Artificial Intelligence and digital humanities paves the way to the pivotal transformations in the 21st Century. New technologies and AI tools are being used for assistance in writing and analysingtext through digital tools, which are stepping into the educational sector. The borders separating digital computation and humanistic understandings are reduced. This paper precisely examines the role of AI tools in the field of digital humanities and how they reconstruct the learning process, innovative mind and critical thinking of learners. The study includes some of the theories such as constructionism, universal design for learning, situated learning and cultural history activity theory. These literary frameworks showcase the process of learning through digital mediation, socio-interaction, and a comprehensive environment for learning and collaborative engagement. Moreover, learning through AI in the digital era emphasises knowledge through a collaborative learning approach and aims to enhance the futuristic learning environment. The incorporation of AI in academics fosters the learning and interactions of students as well as protects the emotions, critical thinking and cultural understandings when supervised by the moral frameworks and thoughtful pedagogy. This paper keenly sums up with the futuristic recommendations for academicians, scholars and industrialists seeking to maintain the balance between human and non-human intelligences in the digitalised era.

  3. Suman Sutradhar, Sulagna Chakrabarti, Sukumar Roy, karforma, J., Saha, S. and Bandyopadhyay, S.
    ABSTRACT:

    Artificial neural networks (ANNs), are computer based mathematical processing systems inspired by the biological neural networks on which the animals brain works and is being used by state of the art computer technology for faster computing systems. In this paper this advanced computing system has been utilized for forecasting rainfall, maximum and minimum temperature during summer monsoon months from ANN models that has been generated by inputting 8 years(2014 to 2021) relevant and available meteorological data. Rainfall amount, maximum and minimum temperature in summer monsoon months are important inputs for crops in kharif season, and if forecasted with accuracy with substantial lead time, then it will be helpful in optimization of crop yield which subsequently will boost the economy of our country. The rainfall, maximum and minimum temperature of year 2022 & 2023 of summer monsoon months was predicted by five best fit models by using twelve meteorological parameters data of previous day and the results found were encouraging. ANN-based forecasting model formula has been created by constructing three layer networks. The data, on analysis, revealed small deviation in forecast values during the event of normal rainfall, maximum and minimum temperature and the model captures nicely the normal trend except in the event of sudden steep change of occurrence of rainfall or maximum and minimum temperature, in which case ensemble forecast of NWP and ANN can be explored.

  4. Lourenço Kwenda
    ABSTRACT:

    O presente artigo científico analisa o impacto do Instituto de Defesa Nacional (IDN) na preservação da Defesa e Segurança Nacional em Angola, destacando o seu papel na formação estratégica de quadros civis e militares, na consolidação das Políticas Públicas de Defesa e Segurança Nacional e no fortalecimento do Sistema de Segurança Nacional. A investigação adopta uma abordagem qualitativa, baseada em revisão bibliográfica, análise documental e enquadramento jurídico-institucional angolano. Conclui-se que, num contexto marcado por desafios como o terrorismo, o crime organizado transnacional, a cibercriminalidade e as ameaças híbridas, o IDN assume-se como um centro de excelência para a produção de conhecimento estratégico e para o fortalecimento da soberania nacional, através da andragogia e estratégias lineares por se constituir um pilar essencial na consolidação da Defesa e Segurança Nacional em Angola, contribuindo para a estabilidade institucional, a preservação da paz e o desenvolvimento sustentável do país. o IDN afirma-se como pilar basilar e fundamental na promoção da cultura estratégica, na articulação interinstitucional e na capacitação técnica para a governação da segurança, contribuindo directamente para a estabilidade, soberania e desenvolvimento nacional.

  5. Dr. Bhola Nath Thakur
    ABSTRACT:

    The classical theory of gyrostat motion in a gravitational environment is often articulated within Newtonian mechanics by Euler–Poisson equations. Nevertheless, when velocities approach relativistic thresholds or when the gravitational field is sufficiently intense, relativistic corrections must be incorporated. In this study, we formulate a mathematical framework that characterizes the motion of a gravitational gyrostat, incorporating relativistic corrections derived from the post-Newtonian approximation of general relativity. The relativistic alteration of the rotational equations of motion is obtained by integrating spin–orbit coupling, relativistic torque, and gravitomagnetic influences. Energy techniques and perturbation theory are used to look at how stable steady rotations are. The study explores that relativistic corrections add new precession terms and change the criteria for stability at equilibrium. These effects are important for astrophysical objects like rotating satellites, compact stars, and spinning spacecraft that are in strong gravitational fields.

  6. N’guessan YAO, Adagba OBODJI, Ollo SIB, Konan Fabrice ASSOUHO and Senan SORO
    ABSTRACT:

    Okra is a vegetable renowned for its nutritional properties. It helps improve the standard of living of rural populations in Côte d'Ivoire. However, okra cultivation faces a major challenge in the form of the pest Podagrica decolorata. The aim of this study is therefore to assess the damage caused by P. decolorata in both the dry and rainy seasons over two consecutive years with a view to proposing effective control strategies at specific times. Sampling was carried out on 32 central plants, eliminating the plants at the edges. The study revealed that P. decolorata attacks all parts of the okra plant, with a preference for the leaves, with an attack rate of up to 100% at the flowering-fruiting stage. The extent of damage to the leaves revealed that in the dry season, the leaves are heavily attacked by P. decolorata at the pre-flowering and flower bud stages. The results of this study offer a good perspective in the control of this pest and thus improve okra production in Côte d'Ivoire.

  7. Nkuina Christophe
    ABSTRACT:

    Climatic responsive building aims to mediate exter¬nal agents both to reduce climate loads and to create a healthy and comfortable indoor environment.The sensitive approach to comfort gives nowadays more chances to implement passive strategies, especially the use of natural ventilation. Despite the clearly visible change of attitudes towards nature, more analysis often lead to the conclusion that the arising buildings are very rarely based on extensive studies of local bioclimatic conditions. The purpose of this paper is to discuss how the traditional ways of adapting dwellings to the climate are combined with advanced technology The northern and southern regions of Cameroon with the Mousgum huts and traditional chiefdoms respectively will allow us to highlight certain technical identities and constructive traditions that are answers to sustainability.Five important case studies are presented in order to demonstrate that the relevant distinguishing feature of bioclimatic architecture is to go beyond the scheme of low-energy buildings and constructed from renewable materials. It is much more vital for the green design to implement the structures in the ecosystem in such a way that they become an integral part of it. Thus understood bioclimatic architecture is logical, well adapted to the climate and therefore economical.

  8. LI Dajun and Yuhua Deng
    ABSTRACT:

    Driven by the national "Carbon Peak and Carbon Neutrality" strategy and the Ministry of Education's "New Engineering" initiative, the traditional training model for environmental engineering talents faces structural transformation pressure, urgently requiring a shift towards a new engineering paradigm that cultivates interdisciplinary knowledge integration capabilities, outstanding engineering practical abilities, and cutting-edge innovative thinking. Taking the environmental engineering program at Hunan Institute of Technology as an empirical research object, this study identifies core issues in current talent cultivation through systematic investigation and in-depth analysis, including curriculum systems lagging behind industrial technology iterations, scattered practical teaching resources disconnected from real engineering scenarios, lack of interdisciplinary knowledge integration mechanisms, and evaluation orientations emphasizing knowledge memorization over ability innovation. Based on this, a "Knowledge-Ability-Platform" trinity practical and innovative ability training model oriented towards the "Dual Carbon" goals is constructed. Through modular curriculum restructuring, building a "Four-Dimensional Integrated" practical teaching platform, implementing interdisciplinary project-driven teaching, and innovating multi-dimensional dynamic evaluation mechanisms, this model forms a closed-loop system that organically connects the education chain and talent chain with the industrial chain and innovation chain. Over three years of practice have shown that this model significantly enhances students' comprehensive literacy in low-carbon technology application, complex environmental problem-solving, and teamwork, with graduates demonstrating markedly improved employment competitiveness, scientific research transformation capabilities, and social service effectiveness, providing a referable and scalable reform paradigm for cultivating environmental new engineering talents in local application-oriented undergraduate institutions.

  9. Dr. Selin Mary, A.
    ABSTRACT:

    Climate change has increasingly transcended its environmental dimensions, emerging as a critical financial risk with immediate and measurable consequences. Within a single year, climate-related events such as extreme weather, regulatory shifts, and market re-pricing can significantly disrupt financial systems, investment portfolios, and economic stability. This study examines the short-term impacts of climate change on the finance sector, focusing on market volatility, institutional risk exposure, insurance dynamics, and policy-driven financial adjustments. It further explores the implications for investors, financial institutions, and policymakers, emphasizing the urgent need for climate-resilient financial frameworks and adaptive risk management strategies.

Health Sciences

  1. Nafeesathul Misriya, K.S., Sandra Jayachandran, Shabna, K.B., Shazia Thasnim, K.S., Thansiha A.A., John, P.P. and Raslamol, K.
    ABSTRACT:

    Medicinal plants have been widely utilized since ancient times for the treatment of wounds and various skin disorders due to their rich phytochemical composition and multiple therapeutic properties, including antimicrobial, anti-inflammatory, antioxidant, and tissue-regenerating activities. The present study focuses on the pharmacognostic evaluation and formulation of a herbal wound-healing balm using Tectona grandis and Nigella sativa, aiming to develop a safe, effective, and natural topical formulation. Tectona grandis leaves were collected, authenticated, shade-dried, powdered, and subjected to Soxhlet extraction using ethanol, whereas Nigella sativa seeds were processed to obtain volatile oil using a Clevenger apparatus. The obtained extracts were further subjected to preliminary phytochemical screening, which confirmed the presence of important bioactive constituents such as alkaloids, flavonoids, tannins, glycosides, and saponins that are known to contribute to wound healing and antimicrobial activity. The herbal balm was then formulated using coconut oil as a base due to its excellent emollient and penetration-enhancing properties, along with beeswax to provide suitable consistency, and small quantities of clove oil and rose oil for additional therapeutic and organoleptic benefits. The prepared formulation was evaluated for various physicochemical parameters such as appearance, consistency, homogeneity, and Spreadability, and was found to be stable and suitable for topical application. Furthermore, the antimicrobial activity of the formulated balm was assessed against Pseudomonas aeruginosa, and the results indicated significant inhibitory activity, suggesting its effectiveness in preventing wound infections. Overall, the study demonstrates that the combination of Tectona grandis and Nigella sativa in a suitable topical base result in a promising herbal formulation with enhanced wound-healing potential, supporting its application as a natural alternative to conventional wound care products.

  2. Niraj Kumar, Agrawal, B. P., Chauhan, D. K., Singh, K. P., Abhay P. Pandey, Rizvi, A. F., and Divya Bartaria
    ABSTRACT:

    The review deals mainly with the intriguing facts of complex mechanism of interaction of the Gut-microbiota, Blood group antigens and Dietary interventions; further as per charismatic effect of yoga, its role in regulating the human metabolism cannot be denied. On the basis of the extensive work carried on in the past decade, and vast experience of the researchers of the institute, the present review has been sketched to establish a meaningful correlation between Gut-Microbiome, Histo-Blood Group and Diet, with intervening effect ofYoga, useful to evolve a holistic approach to deal with several chronic diseases and health problems.

  3. Dr. G.V. Reddy, Dr.Haranadha Reddy, M. R, Dr. Sarah Fatima, Dr. Thudimilla Shivani, Dr. Soniya Chavan, Dr. ANJANI, V., Dr. Ayesha Sultana, Dr. Boddhireddy Nikita, Dr. Sri Bhavya, K., Dr. Amena Asif, Dr. Ampelly Rishitha, Dr. Lasya SNKP Duggirala and Dr.
    ABSTRACT:

    Background: Dental implants are widely used for the replacement of missing teeth and have shown predictable long-term outcomes when appropriate surgical and prosthetic protocols are followed. However, successful implant therapy requires sufficient alveolar bone volume and stable peri-implant soft tissues. In situations where ridge resorption and thin mucosal phenotypes are present, regenerative procedures may be required to establish a favourable biological environment for implant placement. Guided bone regeneration (GBR) and acellular dermal matrix (ADM) grafting are commonly used techniques to improve both hard and soft tissue conditions around implants (1–3). Case Presentation: A 42-year-old male patient presented with missing maxillary premolars and complained of difficulty during mastication. Clinical and radiographic examination revealed horizontal ridge deficiency and a thin peri-implant mucosal phenotype. Implant rehabilitation was planned with simultaneous hard- and soft-tissue augmentation. Management and Outcome: Two dental implants were placed in the maxillary premolar region. Guided bone regeneration was performed using particulate bone graft material and a resorbable collagen membrane to address the buccal bone deficiency. An acellular dermal matrix graft was also placed to increase soft tissue thickness around the implants. Healing was uneventful, and prosthetic rehabilitation was completed after confirmation of osseointegration. At 12-month follow-up, the implants remained stable with healthy peri-implant tissues and satisfactory aesthetic integration. Conclusion: The combined use of guided bone regeneration and acellular dermal matrix grafting can effectively address both bone deficiency and thin soft tissue biotype, thereby improving peri-implant tissue stability and supporting long-term implant success.

  4. Alice, N. C., Jolly Joseph, Tincy Sebastian, Dr. Blessy Peter, Roy K Sebastian Dr. Prachi Chaturvedi, Jeeva Treesa Jojo, Delna Mathew, Cippy Elizabeth Biju, Christeena Joseph, Deena Jose, Dona Maria Babu, Dona Mathew and Jibina Thankachan
    ABSTRACT:

    The present study was undertaken to assess the Knowledge regarding developmental milestones among mothers of under five year children attending pediatric outpatient department in SH Medical Centre Hospital, Kottayam. The study was conducted among 60 mothers of under five year children in SH Medical Centre Hospital, Kottayam. Descriptive survey design was used for the study, subjects were selected using stratified random sampling technique. The tools used for study were socio personal data and structured questionnaire to assess the knowledge regarding developmental milestones among mothers of under five year children. The data collected from 26/07/2023to 28/07/2023 were analyzed using descriptive and inferential statistics. The results revealed that 63.3 % mothers of under five children have average knowledge and 35% had poor knowledge and 1.7% had good knowledge. A statistically significant association was found between knowledge regarding developmental milestones among mothers of under five year children with educational status. No statistically significant association was found between knowledge with age of mothers, number of children, occupation.

  5. Uma Sankar Akula, Nabanit Kumar Jha, Nagadharshan Devendra and Suresh Bidarkotimath
    ABSTRACT:

    Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is a chronic immune-mediated disorder of the gastrointestinal tract characterized by episodes of inflammation and ongoing tissue damage. Standard medical treatments, such as corticosteroids, immunomodulators, and tumor necrosis factor (TNF) inhibitors, have improved patient outcomes but are limited by incomplete responses, systemic immunosuppression, and side effects. Anti-integrin therapies offer a targeted method that specifically blocks leukocyte movement into the intestinal mucosa. Integrins are cell adhesion molecules that facilitate immune cell migration and tissue infiltration. By blocking the interaction between leukocyte integrins and endothelial cell adhesion molecules, anti-integrin agents prevent inflammatory cells from entering the gastrointestinal tract. Currently approved anti-integrin drugs for IBD include natalizumab and vedolizumab, with newer options like etrolizumab under research. These medications demonstrate significant success in inducing and maintaining remission in patients with moderate to severe IBD. Notably, gut-selective agents such as vedolizumab provide enhanced safety by reducing systemic immunosuppression. This review explores the pharmacological mechanisms, pharmacokinetics, clinical effectiveness, safety profiles, and emerging therapeutic roles of anti-integrin therapies in inflammatory bowel disease.

  6. Bréhima KEITA , Mohamed M TALL , Cheick O KAMISSOKO, Nourou TRAORE , Kaly KEITA, Hassana TAPILY, Cheick A DIARRA , Aboubacary KONATE , Inhissa BENGALY and Maimouna. TRAORE
    ABSTRACT:

    Context: Hospital reception is a major determinant of user satisfaction and access to care. In Mali, despite a favorable legislative framework, the Gabriel Touré University Hospital faces chronic user dissatisfaction. Objective: This study aims to analyze the root causes of poor patient care and to propose a budgeted strategic improvement plan. Methods: A participatory action research project was conducted from August 2024 to February 2025. It involved 131 patients, 76 staff members, and a nominal group of 30 experts. Quality management tools ( Hanlon model , Ishikawa diagram, multi-criteria decision matrix) were used to prioritize problems and develop solutions. Results: "Unsatisfactory patient care conditions" were identified as the priority problem ( Hanlon score : 475). Causal analysis (5Ms) revealed the predominance of factors related to the workforce (insufficient and untrained staff) and organization (lack of procedures, inadequate signage). An action plan of 37.3 million FCFA, focused on the recruitment of 23 agents and the training of 46 staff members, has been validated. Conclusion: Improving customer service requires a systemic approach. Rigorous implementation of the proposed action plan should enable a satisfaction rate exceeding 80% by 2027.

Social Sciences and Humanities

  1. Reverend Professor Willis Inghabo Otuya
    ABSTRACT:

    This study examines the practice of social entrepreneurship among owner-managers of cottage industries in Kakamega County, with a specific focus on how social entrepreneurial orientations influence employee outcomes in small and medium enterprises (SMEs). Drawing on a sample of 138 SME employees from cottage industries operating within Kakamega County, 100 completed questionnaires were returned and analyzed. Using structural equation modeling, frequency distributions, correlation analysis, and binary logistic regression, the study investigated the relationship between social entrepreneurship practices—particularly those targeting employee welfare—and perceived enterprise performance. Findings reveal that social entrepreneurship practices, including employee well-being initiatives, fair labor practices, and community-oriented hiring, serve as significant predictors of enterprise performance among cottage industry SMEs in Kakamega County. The study contributes to the growing body of literature on social entrepreneurship in developing country contexts and offers practical implications for owner-managers seeking to balance social mission with business sustainability.

  2. Mimine Akissi Hien, Dr. Yacouba Tengueri and Dr. Alexis Clotaire Némoiby Bassolé
    ABSTRACT:

    Background: Bridewealth constitutes a foundational element of customary marriage in sub-Saharan Africa. Among the Lobi of the canton of Gaoua (Burkina Faso), it is perceived by non-Lobi communities as financially inaccessible, thereby generating intercommunal tensions. Objective: This study analyses the transformations undergone by bridewealth practices within the Lobi community under the influence of modernity and cultural intermingling. Method: A qualitative approach was adopted, grounded in semi-structured interviews conducted with Lobi households, customary and religious authorities, as well as migrant populations residing in the canton of Gaoua. Results: The findings reveal a progressive monetisation of the constituent elements of bridewealth, notably livestock and agricultural labour, under the influence of urbanisation, migration, wage employment, and the individualisation of social relations.

  3. Dr. Dashrath Singh Nag
    ABSTRACT:

    The rapid advancement of Artificial Intelligence (AI) is transforming the information landscape and redefining the roles and responsibilities of library professionals. From automated cataloguing, intelligent discovery systems, and chatbots to predictive analytics and personalized user services, AI technologies are increasingly embedded in library operations and services. This chapter examines the impact of AI on the future of library professionals, focusing on how traditional roles are evolving into technology-enabled, data-driven, and user-centric functions. It explores emerging competencies such as AI literacy, data stewardship, algorithmic awareness, and ethical decision-making, which are essential for librarians in the digital age. The chapter also discusses challenges associated with AI adoption, including bias, data privacy, transparency, workforce reskilling, and the digital divide. By highlighting real-world applications and future trends, the study emphasizes the need for continuous professional development and institutional support to ensure that library professionals remain relevant and resilient. The chapter concludes that AI should be viewed not as a replacement but as an augmentative tool that empowers library professionals to enhance access to information, improve service quality, and strengthen their role as facilitators of knowledge in an AI-driven society.

  4. Carlos Javier Hernández Hernández, Leodan Tadeo Rodríguez Ortega, Judith Callejas Hernández and Alejandro Rodríguez Ortega
    ABSTRACT:

    Los dípteros de la familia Muscidae, Oestridae y Calliphoridae, son insectos con potencial sinantrópico, tienen importancia zootécnica, sanitaria y económica en los sistemas de producción animal del Valle del Mezquital, estado de Hidalgo, México. Se caracteriza por tener una fuerte producción de ovinos. El objetivo de este trabajo fue investigar las especies de dípteros con potencial de infestación en los sistemas de producción ovina para el Valle del Mezquital, además, para que los profesionales de la producción animal puedan reconocer el ciclo biológico de las diferentes especies de mayor distribución e impacto sanitario y económico en esta región agroclimática y considerar establecer programas de manejo integrado de esta plaga para que contribuyan a la sustentabilidad en la producción pecuaria. Además, se incluye la mosca del Gusano Barrenador del Ganado (Cochliomyia hominivorax) que presenta una potencial plaga con la capacidad de infestación debido al nuevo registro de emergencia sanitaria desde noviembre de 2024.

  5. Dr. Tazuddin, S.M.
    ABSTRACT:

    This study explores the impact of Community-Based Tourism (CBT) on the economy of Bangladesh, focusing on the Khulna (Sundarbans) and Kushtia (Lalon&Khuti bari). CBT is a community-owned tourism model designed to foster economic development through the preservation of local culture and nature. Utilizing a primary survey of 50 participants alongside secondary data, the research evaluates how CBT influences income, employment, and poverty alleviation. Key findings indicate a significant positive shift in the demographic and economic status of participants. After joining CBT programs, unemployment among respondents plummeted from 42% to 6%, while self-employment rose from 26% to 50%. Income levels also saw substantial growth, with 44% of respondents moving into the Tk. 21,000–30,000 annual net income bracket and 84% reporting that their income had become sufficient to meet their needs. Despite these gains, the study identifies challenges such as the fragile state of the national tourism industry and lower participation rates among women and older age groups. The research concludes that with integrated national policies, public-private partnerships, and improved infrastructure, CBT can serve as a vital tool for sustainable rural development and foreign exchange earnings in Bangladesh.

  6. Amiran Berdzenishvili and Kakha Ketsbaia
    ABSTRACT:

    The article discusses the formation and development of sociology as a science studying society in Georgia. The contribution of Georgian scientists and public figures is shown. It is noted that Ivane Javakhishvili stands at the head of the University School of Sociology in Georgia, and Acad. Paata Gugushvili is one of the founders of the Academic School of Sociology (it should be noted that there are not many founders of sociology in Georgia).

  7. Awandia Joseph Tazitabong and Adu Margaret Owah
    ABSTRACT:

    The study was aimed at investigating the relationship between gender stereotype and students’ psychological wellbeing in the University of Buea. The study was guided by two research objectives which were to; find out how teachers attitude affects students’ psychological wellbeing and to determine how students’ self-esteem affects their psychological wellbeing. This study employed the convergent parallel design. The population of the study was made up of all the undergraduate students and lecturers teaching undergraduate from the University of Buea. The target population consisted 8254 undergraduate students from two selected faculties and a college, The accessible population was made up of 1222 level 200 students. The sample size was 260 students selected using simple randomly sampling technique and 9 lecturers were selected using purposive sampling technique. The data were collected using a questionnaire that was made up of close-ended items for students and an interview guide for lecturers. Data we reanalysed inferentially and thematically, For the inferential statistics, Pearson product moment correlation coefficient was used to analysis the data while the qualitative data were analysis using thematic analysis.Findings showed that there is a significant and positive relationship between teacher attitude and students’ psychological wellbeing. The positive sign of the correlation value implies that the psychological wellbeing of student increases when their teacher’s attitudes toward them are positive, findings also showed that there is a significant and positive relationship between self-esteem and students’ psychological wellbeing. The positive sign of the correlation value implies that the students’ psychological wellbeing increases when their self-esteem is positive. Based on the above findings, it was recommended that; training should be organize on gender sensitive techniques through workshops for teachers to change their attitudes and behaviours toward all gender and government should develop and implement gender sensitive polices in all academic institutions.

  8. Ritika Jha, Ju-Hui Wei and Hsien-Ming Lin
    ABSTRACT:

    Drawing on work/family border theory, this study aims to investigate the academic challenges experienced by mother students in India and their coping strategies for balancing academic and family roles. It will also explore how boundary integration and border keepers help Indian mother students balance these roles. A qualitative exploratory approach was adopted, and in-depth individual interviews were conducted with seven mother students in India as participants. The transcribed data were analyzed using thematic analysis. The results showed that time constraints, low technical competency and academic adjustment problems were the main hindrances faced by these students. The flexibility of online learning, family prioritization, benefits of higher education and support from husbands, family members, peers and teachers facilitated work/family balance. The findings indicate that boundary integration facilitates greater work/family balance than segmentation. A flexible curriculum would aid in balancing these roles.

  9. Dr. Sachita Nanda Sa
    ABSTRACT:

    Since India's economic liberalization in 1991, government spending on infrastructure and public health services—which aims to promote fair access—has changed significantly. Due to disparities in budgetary resources and policy priorities, Indian states exhibit significant variability in their spending patterns as primary healthcare providers. With a focus on interstate inequalities, equity concerns, and the impact of public funding on health outcomes, this study examines changing public health budget trends in 15 key states over the post-reform era. It examines changes in budgetary allotments, per capita expenditures, and the ratio of revenue to capital expenditures using state-level data. The results show unequal progress, with wealthier states in a better position to support health services and infrastructure while poorer states must contend with competing demands for growth and budgetary limits. Essentially, the main challenge facing post-reform India is not only increasing overall public health spending but also allocating it fairly among states in order to promote a stronger, healthier nation. For consistent growth in the health sector, policy recommendations emphasize more fiscal devolution, targeted expenditures, and strong institutions.

  10. Suchismita Neogi
    ABSTRACT:

    Rachel Yoder's Nightbitch (2021) dissects the pathologisation of the maternal body under medical patriarchy, exposing how postpartum identity is fragmented and policed through clinical discourse. The novel's protagonist, transforming into a canine hybrid amid motherhood's corporeal demands, embodies feminist critiques of gynaecology as an extension of patriarchal control, where lactation, rage and bodily rebellion are recast as psychotic symptoms rather than valid responses to isolation and erasure. Drawing on theorists like Adrienne Rich and Susan Bordo, this analysis reveals how medical interventions such as therapy and pharmaceuticals reinforce normative femininity, stripping agency from the maternal subject while ignoring structural inequities like spousal detachment. Yoder subverts this through the narrator's feral reclamation, asserting a hybrid postpartum self that defies pathologisation. Ultimately, Nightbitch challenges the medical gaze, advocating embodied maternal knowledge beyond diagnostic confines.

  11. Chiranjit Mandal, Gopal Chandra Mura, Sumit Mondal and Dr. Manikanta Paria
    ABSTRACT:

    This study explores the moral values integral to the Vedic education system of ancient India and their influence on both individual moral development and broader societal values. Grounded in sacred texts such as the Vedas, Upanishads, and Bhagavad Gita, the Vedic system emphasized key ethical principles, including Dharma (righteousness), Ahimsa (non-violence), Satya (truth), and Karma (action and its consequences). These values were not only taught through the study of sacred texts but were also integrated into daily life through the Guru-Shishya (teacher-student) relationship, wherein the Guru served as both an academic and moral guide. The Guru's role was pivotal in shaping the student’s character, teaching by example and providing personal mentorship. This paper explores how these moral teachings influenced personal behaviour and contributed to societal norms, fostering social harmony, ethical leadership, and cultural stability. By reviewing secondary literature, the study underscores the lasting impact of Vedic moral education, suggesting its relevance to contemporary discussions on character development, ethics, and social responsibility. Ultimately, the Vedic system provided a model of education that merged intellectual and moral growth, promoting a just and ethical society.

  12. Shaista Parween
    ABSTRACT:

    Studying the trends in indirect tax revenue, Consumer Price Index (CPI), and inflation before and after GST implementation is essential to evaluate the reform's success in unifying the economy, ensuring fiscal stability, and protecting consumer purchasing power. The objective of this paper is to identify the trend and to study the propensity of price changes before and after GST by employing Model comparison using Regression analysis the different models (Linear, Quadratic and Exponential) has been considered. The data is collected from government website of Department of revenue, Ministry of finance, which provided yearly data for indirect taxes estimates, and Consumer Price Index (CPI) data and inflation rates are obtained from monthly publications by Central Statistics Office, Ministry of statistics and Programme Implementation (MOSPI) and using this secondary data average yearly values are calculated. The period of study is 10 years consisting of five years before the adoption of GST (2012-2017) and five years after the adoption of GST (2017-2022). The findings shows exponential model is the best fit for both periods, indicating a steady increase in indirect tax revenue and inflation rates. The higher R-squared values for the period before GST suggest that the models were better suited to the economic conditions before GST implementation.

  13. Dr. Hossain, K.A.
    ABSTRACT:

    Many of us dream of moving abroad or visiting foreign lands. Therefore, useful information, experiences, ideas, reports, and data on the best countries worldwide especially in Asia can greatly assist those interested in travel or relocation. This paper aims to support travelers and potential residents in selecting the best destinations, helping them make informed decisions. Asia is known for its lively climate, spiritual depth, nature, rich culture, history, vibrant lifestyle, and incredible biodiversity, making it a top choice for many travelers. From pristine beaches and lively cultures to UNESCO World Heritage-listed cultural capitals, the region offers adventure, relaxation, peace, happiness, diversity, activities, delicious cuisine, comfortable living, and warm hospitality. Asia is truly a land of the exotic, where elephants’ cross riverbeds, pagodas tower over terraced rice fields, and famous sites include the Great Wall of China, Malaysia’s atolls, India’s royal palaces, and Nepal’s Himalayan ranges. Its landscape features diversity, safety, remarkable history, and beauty, especially in Japan. However, since Asia is so vast, we can’t visit all the countries at once. To make planning easier and prioritize our travels or life choices, this investigative paper will serve as a helpful guide for interested people for decision making.

  14. Dr. Karthikeyan, T. and Mr. Binukumar, M
    ABSTRACT:

    The development should be always for the betterment of people without affecting the environment, it should not harmful to the earth. This initiative is called Green Economy Development. But real-world concern is how to make development without depleting the resources, especially scarce resources. So, finding an optimum level is the need of the hour. Nowadays Green Economy, Sustainable Development are the buzz words, thanks to SDGs.In 2015 all UN member nations were adopted the 17 world Sustainable Development Goals.The purpose of this article is to present and analyse how to reduce the gap in Green Economy and Sustainable Development. Here we require the fostering development must not deplete the natural resources. Even in marketing we adopt societal marketing concept, selling a product must be beneficial for at least three parties, it should give profit for the producer, value for the buyer and benefit for the society. So, in every development, society must get its share. This paper focuses its attention on the Green initiatives taken by the Kerala Government and its impact on Sustainable Development.

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