Aflatoxins (AF), the toxic secondary metabolites produced by Aspergillus flavus and Aspergillus parasiticus, are a major concern in the poultry production. The dietary aflatoxins reduce weight gain, feed intake, and increase feed conversion ratio. Aflatoxicosis significantly reduced the carcass traits. Affected birds show poor vaccine response and low antibody titre, as both cellular and humoral immunities are affected .Although numerous detoxification methods have been tested, none seems able to fulfill the efficacy, safety, safeguarding of nutritional elements and costs requisites of a detoxification process. This paper reviews the detoxification methods by using esterified glucomannan (Mycosorb) in aflatoxicated birds