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An investigation was carried out to analyze the antipyretic activity of the marine mollusc Babylonia spirata. Methanol extract of Babylonia spirata was subjected to antipyretic activity on Wistar albino rats by Brewer’s yeast induced pyrexia. The extract when administered at a dose of 400mg/kg body weight caused significant antipyretic activity by lowering the body temperature (37.12±0.13) at 3 rd hour compared to standard drug paracetamol (37.51±0.14). The methanolic extract of Babylonia spirata at the concentration of 200mg/kg and 400mg/kg showed a significant (P<0.05) antipyretic activity.
Rosane Cavalcante Fragoso, Brasil
Chief Scientific Officer and Head of a Research Group
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