Assessment of clinical spectrum of posterior reversible encephalopathy syndrome (pres) amongst patients of eclampsia

Background: With availability of neuroimaging, it is possible to know the exact underlying CNS pathology in eclampsia and thus therapy can be targeted at the same. This study was undertaken to assess clinical spectrum of PRES syndromes amongst patients of eclampsia. Objective: The aim of present study is to assess clinical spectrum of PRES syndrome amongst patients of eclampsia. Methodology: This observational study was carried out in department of Obstetrics & Gynaecology at Sir T Hospital, Bhavnagar from june 2020 to September 2021. A total of 36 patients who were admitted for eclampsia were studied. After stabilisation of patients, a detailed history and examination of patients done and patients were sent for MRI and findings of PRES were studied. Results: Majority of patients were in the age group of 20-24 years. Maximum incidence was seen with primigravida (66.7%). Almost all patients of eclampsia were presented with generalized tonic clonic convulsions (88.5%) followed by headache (52.7%). Majority of patients were admitted with systolic blood pressure of ≥161 mmHg. 94.4% women with eclampsia had PRES in MRI. Occipital lobe of brain (77.7%) is mostly affected followed by parietal lobe (69.4%). Convulsion (88.2%) is most common in PRES followed by headache (55.8%). There was case fatality rate of 5.56% in this study with 2 maternal mortality. Most of neonates were admitted in NICU (42.7%) because of prematurity. Conclusion: Diagnosis of eclampsia is clinical and involving neuroimaging. The characteristic imaging findings and high index of clinical suspicion along with radiological correlation, will help in early recognition and prompt management of PRES, which will aid in preventing grave complications.