Various samples of groundwater were collected from different areas in and around Kolleru Lake and analyzed for their physicochemical characteristics. The results of this analysis were compared with the water quality standards of WHO and CPHEEO. In this analysis the various physicochemical parameters such as PH, total dissolved solids, Ca, Mg, Na, No3, K, Cl, So4 and HCo3 etc., determined using standard procedures. The quality of groundwater samples were discussed with respect to these parameters and thus an attempt were made to ascertain the quality of groundwater used for drinking and domestic purposes in the sampling areas.