The association of Grave disease of with the syndrome of Gougerot remains rare. The purpose of the presentation of this observation is to make it a meta-analysis through the literature and to work towards an early treatment. We are reporting a case of Myasthenia associated with a syndrome of Gougerot-Sjögren in a 32-year-old patient that were lately diagnosed. The diagnosis was retained in front of the myogenic syndrome with muscular deficit, a left (awkward) unilateral ptosis on the left side, a poly arthralgia and a Sicca oculo-buccal syndrome. These signs were associated with a positivity of antibodies. This association seems exceptional. A Good therapeutic result was first obtained with the triple prostigmine-prednisolone-azatioprin association.
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