Blockchain technology is a decentralized digital system that is increasingly explored in healthcare for its ability to improve data security, transparency, and trust. Initially developed for cryptocurrency transactions, it is now applied to manage sensitive medical information. Healthcare relies extensively on digital data, including electronic health records, diagnostic images, and research data; however, traditional centralized systems face challenges such as cybersecurity risks, data tampering, poor interoperability, and privacy concerns.1,2,3 In dentistry, particularly periodontics, accurate and longitudinal documentation of clinical parameters, radiographs, treatment outcomes, and inflammatory biomarkers is critical for disease monitoring and research. Blockchain provides a tamper-proof distributed ledger, ensuring data integrity and reliability of dental records.1,2,4 Blockchain further enables secure data sharing through cryptographic access control and smart contracts, which can automate informed consent and ensure ethical compliance in clinical practice and research. In periodontal research and clinical trials, blockchain enhances transparency by permanently recording protocols, consent, and outcomes, thereby reducing reporting bias.5,6 Additionally, blockchain-supported datasets can improve the quality of artificial intelligence models for periodontal risk assessment and personalized treatment planning. Despite limitations such as implementation cost, scalability, and regulatory challenges, blockchain holds promise for advancing dental and healthcare data management through interdisciplinary collaboration.3,5,6
