Candidemias in hospitalized patients of the baixada fluminense region, province of rio de Janeiro, Brazil

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Author: 
Maria da Penha Laprovita Oliveira, Antonio Neres Norberg, José Tadeu Madeira de Oliveira, Fabiano Guerra Sanches, Rodrigo Fernandes de Freitas and Nicolau Maués Serra Freire
Subject Area: 
Health Sciences
Abstract: 

Sepsis by Candida species are nowadays one of the leading causes of morbidity and mortality, especially in hospitalized, immunocompromised patients and newborn with high health risk levels. The objective of this research is to investigate the incidence of candidemias in patients hospitalized at the Baixada Fluminense region, Province of Rio de Janeiro, Brazil, and identify species of the genus Candida which causes sepsis on these patients. Blood samples from 1213 patients with clinical suspects of sepsis were collected between January 2010 and December 2014 and seeded on the nutrient broth Brain Heart Infusion. Positive cultures for yeast cells were transplanted into Sabouraud dextrose agar medium and the fungal growth obtained was identified by biochemical tests of BioMerieux–Vitek system. 31 cases of candidemia were diagnosticated, which corresponded to a prevalence rate of PC =2,56. The isolated species of the genus Candida were: 14 cases of Candida albicans (Dominance Coefficient , DC=45,16%), two cases of C. krusei (DC=6,45%), four cases of C. stellatoidea (DC=12,90%), one case of C. glabrata (DC=3,23%), two cases of C. parapsilosis (DC=6,45%) and eight cases of C. tropicalis (DC=25,81%). The results highlighted the need for continued attention to patients hospitalized to possible infections by Candida species which causes candidemias.

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