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Characterization of novel Co(II)transition metal complex of ONO donor ligand derived from glutaraldehyde and l-histidine and its screening for toxicity against fungal and bacterial speciesh round data

Author: 
Ajith Sinthuja, S.
Subject Area: 
Physical Sciences and Engineering
Abstract: 

Coordination complex with metal ion Co(II) has been synthesized from the Schiff base (L) derived from glutaraldehyde and L-histidine. Both the ligand and the complex synthesized were characterised by elemental analyses, magnetic susceptibility, molar conductance, IR, UV-Vis, 1H-NMR spectral studies, X-ray diffraction study, SEM study and thermal studies. On the basis of the above studies, it is proposed that the ligand is suggested to act in a tetradentate manner coordinating through both carbonyl oxygen and amino nitrogen atoms. The antimicrobial activities of the ligand and its complex were screened by Disc Diffusion method. The activity data shows that the metal complex is more potent than the parent Schiff base ligand against bacterial and fungal species.

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