
Superficial fungal infections of skin affect millions of people throughout the world. The information of medicinal plants has been accumulated in the course of several centuries based on various medicinal systems such as Ayurveda, Homeopathy, Naturopathy, Modern, Siddha and Unani. Enicostema axillare is a common Indian medicinal plant belonging to the family Gentinaceae was selected and screened for the phyto chemical compounds, antifungal activity and clinical evaluations. Samples collected from the skin infected patients and the patients were treated with plant drug Vellarugu chooranam (Enicostema axillare). The anti fungal activity was studied only on the predominant fungal pathogens Trichopyton rubrum and Trichophyton mentagraphytes.