The success of the endodontic treatment depends upon the fluid tight seal between the intraradicular space and the periradicular tissues, both apically and coronally which should prevent microleakage. In some cases according to periapical conditions indicated for periapical surgery where in this procedure includes exposure of involved apex by flap reflection, removal of necrotic tissue, resection of the apical end of the root, root end preparation and placement of retrograde filling restorative material. Ideally retrograde filling materials should be biocompatible, easy to manipulate, radiopaque, dimensionally stable and non resorbable. It should not be affected by presence of moisture and should be adhesive to dentin, nontoxic, well tolerated by the periradicular tissues as well as promote healing.
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