Freshly prepared coconut milk (25%, 50% and 100% preparations) was administered to mice in three test groups for 14 days. The control group was given an equal volume of tap water for the same period. Consumption of the different concentrations of coconut milk was found not to alter significantly (p>0.05) the serum lipid profile and pro-atherogenic indices of mice in the test groups, relative to the control group. Coconut milk may not increase the cardiovascular disease risk of those who consume it for food or for its medicinal values