Objective: Endocrown restorations are single unit prostheses fabricated from reinforced ceramics. These restorations are indicated for endodontically treated teeth, molars especially, that have significant loss of coronal structure. Endocrowns gain their retention from the coronal portion integrated into the apical projection that fills the pulp chamber space, and possibly the root canal entrances. Clinical Consideration: In this case report a new style Fixed Partial Denture is introduced. Here mandibular second molar had compromised tooth structure and hence Endocrown was planned with the tooth. For replacement of missing first molar a three unit fixed partial prosthesis was planned. This unique three unit prosthesis had Endocrown on mandibular second molar and a full veneer crown on mandibular second premolar as an abutment fabricated in Zirconia with CAD-CAM technology. Conclusion: This innovative design of Fixed Partial Denture is better suited in cases where there is compromised tooth structure and the tooth is strategically important and has to be retained.