The importance of healthful school environment in the enhancement of effective teaching and learning cannot be overemphasized. It is a fact that adequate physical structures in a school not only enhance greatly the efficiency and proficiency of teachers but also facilitate good understanding and comprehension on the part of the learners. Thus, a good and healthful school environment enhances effective learning, imperative for the realization of educational objectives and, therefore, economic growth and development and social transformation of the society. Based on this, this paper considers: the concepts of teaching and learning, healthful school environment, and the relationship between healthful school environment and effective teaching and learning. It then recommends that professional educational planners should be involved in school planning; that educational policies should not be mated up with political interests; and that non-government organisations should assist the government to provide adequate structures for effective teaching and learning.