CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Evaluation of AgNOR staining using exfoliative cytology in oral squamous cell carcinoma

Author: 
Hitasree, B. N., Malathi Manne, Shivani Neelam, Syed Afroz Ahmed, Charu Suri, Shahela Tanveer and Shravan Kumar
Subject Area: 
Health Sciences
Abstract: 

Introduction: Oral squamous cell carcinoma encompasses all malignancies originating in the oral cavity and there is need for improvement in early detection of oral carcinomas because treatment is more effective and the morbidity is minimal. Cytological study of oral cells is a non-aggressive technique that is well accepted by patients and an attractive option for early diagnosis. AgNORs study provides understanding of the tumoral behavior since their frequency, size and cell arrangement have been reported as a discriminatory factor between certain suspected lesions. Aim: The aim of the present study was to evaluate the acidic, argyrophilic, nonhistonic proteins by using silver-staining AgNOR technique in exfoliated cells and to compare in normal oral mucosa and oral squamous cell carcinoma. Materials And Methods: Exfoliative cells were obtained from 25 cases of oral squamous cell carcinoma and 25 cases of normal mucosa by using wooden spatula. After staining, 100 epithelial cells were randomly selected and counted by using oil immersion at 1000x magnification. Student’s independent t-test was used for data analysis. Result: The mean AgNORs count per nucleus was found to be 4.46 in oral squamous cell carcinoma group and 2.84 in normal mucosa with a p-value (<0.0001) and was statistically significant. Conclusion: Thus the present study suggested that, the silver staining technique used for the detection of NORs in conjunction with exfoliative cytology is an easy, non-invasive and accurate screening method for the detection of clinically suspicious oral cancerous lesions. Because of its simplicity and high reliability for cellular proliferation, AgNOR staining with oral smears can be used as an adjunct to the other cytological diagnoses for the early detection of oral cancer.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran