Evaluation of phenylalanine ammonia lyase between petroselinum crispum and rhodosporidium toruloides based on computational algorithms

In this study, Phenylalanine ammonia lyase (PAL) was evaluated as one of the important enzymes in the pathway of phenylpropanoids synthesis in order to understand the structural fold and sequence homology; so that it was extracted from Protein Data Bank (PBD): X-ray crystallographic structures of Rhodosporidiumtoruloides (1T6J) as a genus of fungi category and (1W27) Petroselinumcrispum as a genus of plants category. In order to structural analysis of PAL has been used some software include Protein Structure Comparison Tool V 1.4, on-web PDBe version based on secondary structure matching (SSM) and Combinatorial Extension(CE) for Structure Alignment, calculation of statistical indicators such as Z-score, p-value, Q-score and etc. Finally PAL showed a significant relationship between structural sequences of 1T6J & 1W27 in terms of structural folds similarity and partialhomology with calculated indices between the two enzymes.