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Evaluation Of Phytochemical And In Vitro Antibacterial Activities Of Organic Solvent Fractions Of Ganoderma Lucidum Methanolic Extract

Author: 
Shamaki B.U (b) S., Sandabe, U.K., Abdulrahman, F.I and Ogbe, A.O and Geidam, Y.A.
Subject Area: 
Life Sciences
Abstract: 

The phytochemical and antibacterial activity of different organic solvent extracts (methanol, Ethyl acetate and N-butanol), of the wild mushroom- Ganoderma lucidum was evaluated at different concentrations 200mgml-1, 150mgml-1, 100mgml-1, 50mgml-1 and 25mgml-1. The antibacterial activities of the extract were investigated using the disc diffusion method. All the test microbes showed resistance against methanolic and N-butanolic fractions. However, they all showed susceptibility to ethyl acetate extract fraction except Streptococcus faecalis, Escherichia coli and Enterobacter aeroginosa that showed resistance. The Ethylacetate extract fraction exhibited broad spectrum of activity by acting against both gram positive and gram negative bacteria. The inhitory effect of the test extract was compared with a standard antibiotic-AmpicloxR (Ampicillin + Cloxacillin).The extract showed its potentials as an antibacterial agent that should be exploited.

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