The present study was aimed at to investigate the bioactive compounds from the leaf and root extracts of Hypochaeris radicata using GC-MS analysis. 11 compounds from leaf and 9 compounds from root extracts were identified. The major chemical constituents in leaf and root extracts are phytol, acetate (19.22%), hexadecanoic acid, methyl ester (17.37%), 9,12,15-octadecatrienoic acid, methyl ester, (Z,Z,Z)- (16.74%) and phytol (13.60%) and Urs-12-en-3-ol, acetate, (3.beta.) (43.86%) and 1-Benzazirene-1-carboxylic acid, 2,2,5a-trimethyl-1a-(3-oxo-1-butenyl) perhydro-, methyl ester (30.31%). The bioactive compounds in the methanolic leaf and root extracts of the species, H. radicata exhibited the phytochemical importance and hence its therapeutic significance.