Glycine 1.5% is used for optimal visualization during hysteroscopy, but it may cause pulmonary oedema. We are reporting a case of severe and life threatening appearance of Operative hysteroscopy intravascular absorption syndrome during hysteroscopy myomectomy under GA in the Gynecology operation theater. Development of pulmonary oedema, metabolic acidosis and Hyponatremia was very fast forcing us to abandon the procedure and shifting the patient to ICU. Patient was however saved with great efforts by mechanical ventilation, correction of metabolic acidosis, Diuretics, fresh blood transfusion, 7-5% soda bicarbonate, correction of hyponatremia by 3% NaCl infusion, broad spectrum antibiotics and other corrective measures as and when required. Patient was discharged on the 14th day with full recovery.
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