The objective of this study was to evaluate the effect of mineral fertilizer NPK associated with poultry litter biochar on growth initial of sesame cv. BRS Seda. The experiment was carried at city Campina Grande, PB, Brazil, in greenhouse with a completely randomized experimental design, with three replications. The treatments were arranged in a factorial 5 x 4 consisted of five doses of mineral fertilization with N:P:K (D1 = 0:0:0; D2 = 13.5:50:14; D3 = 27.5:100: 27.5; D4 = 41.:150:41.5; D5 = 54.5:200:55 mg kg-1) associated with four doses of poultry litter biochar (0; 20; 40; 55 g kg-1) calculated based on the volume of soil. At 30 and 45 days after sowing were determined plant height, stem diameter, number of leaves by plant, leaf area and dry biomass of shoot. The mineral fertilization promoted increase in plant height, stem diameter, number of leaves, leaf area and dry sesame biomass at 45 DAS, reaching maximum growth with the N: P: K = 50: 150: 75 mg kg-1 of soil. The fertilization with poultry litter biochar promoted reduction of all variables in sesame at 30 and 45 DAS and raised the pH and electrical conductivity of the soil.