Understanding protein modeling is key to protein structure analysis. The current research includes crp salmonella typhimurium protein for modeling. The main criteria in model generation is generation of model based on available structures and then knowing model quality generated in process. Swiss prot gives automated model with model quality estimation by Qmean and Anolea. The other dedicated model quality estimation server used is ProSA. The protein model determination is helping in various protein- protein interaction studies, drug-taget interaction. The removing fear of protein model can give better insight into problems based on interaction study. This step by step research would will promote Research into protein study for biologist who are not well aqucuiented with protein modeling.
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