Castleman’s disease (CD) is an uncommon lymphoproliferative disorder typically presenting as ‘Mediastinal’ lymph node swelling. Clinical presentation can range from asymptomatic to generalised lymphadenopathy and hepatosplenomegaly. Two histological variants are hyaline vascular type and plasma cell type. Hyaline vascular type CD presents as unicentric mass mimicking various infectious and malignant causes of lymphadenopathy. Cytological features vary depending upon the extent of the lesion, thus, fine needle aspiration cytology (FNAC) is not always conclusive and histopathology is required to reach a definitive diagnosis. Here we present a case of unicentric castleman’s disease (UCD) diagnosed on FNAC with histological correlation.
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