Hyaluronic acid is a high molecular weight polysaccharide, which plays a major role in the functioning of extracellular matrices. Its presence has been found in connective tissues and is particularly concentrated in synovial fluid, the vitreous fluid of the eye, umbilical cords. Also it is found in periodontal tissues including mineralized and non mineralized tissues with a greater concentration in non mineralized tissues, such as gingiva and periodontal ligament. Due to its role in inflammatory and healing mechanisms, use of hyaluronic acid has been applied in various fields like ophthalmology, Dermatology, Orthopedics, etc in various therapeutic procedures. Recently hyaluronic acid has been applied in various periodontal procedures for its therapeutic properties. The aim of present review, article is to discuss application of hyaluronic acid in various periodontal procedures.