Iron deficiency anemia is found commonly associated with nutritional deficiency. It has been found in various studies that increase in platelet count or thrombocytosis is seen in patients with iron deficiency anemia. Rarely has it been reported with low platelet count or thrombocytopenia. The cause of thrombocytopenia in iron deficiency anemia is not well understood. In few studies role of iron in platelet synthesis and aggregation is suggested. This case study here presents a case of young man with iron deficiency and thrombocytopenia with no pathological disease related with thrombocytopenia. Further patient’s platelet levels improved to normal with oral iron therapy alone suggesting role of iron in platelet synthesis.