Career change is an issue of concern to institutions given the huge costs related to lost productivity, hiring and training of employees. This study examined the effect of job satisfaction on non teaching staff career change intention in Moi University Eldoret Municipality Kenya. The objective of this study was to; establish the effect of remuneration on non teaching staff career change intention. This study was based on survey research design. Individual elements were selected using stratified, systematic random sampling and the sample size determination was based on Nassiuma method. Data analysis was based on frequencies, percentages, spearman correlation and ordinal regression. The findings indicated that; Remuneration had a significant relationship with non teaching staff career change intention. The findings indicated that non teaching staff considered remuneration as a critical indicator of their perception of job satisfaction. This study concludes that job satisfaction indicator as perceived by non teaching staff had a higher impact on career change intention. Arising from the conclusion of this study, it is recommended that, the institution pay reasonable salaries to its employees, which continue to act as a constraint to performance of its staff resulting to career change intention.