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Neurofibromatosis I with facial plexiform neurofibroma and mandibular hypoplasia. A case report with Review of Literature

Author:

Dr. Preeti Patil, Dr. Venkatesh G. Naikmasur, Dr Kirty Nandimath and Dr. Karthik Kabbur

Subject Area:

Health Sciences

Abstract:

Neurofibromatosis type 1 (NF1, or Von Recklinghausen’s disease) is a genetic disorder transmitted as an autosomal dominant trait with variable expressivities and complete penetrance. It is characterized by a variety of clinical manifestations, including multiple neurofibromas that are associated with a high risk of sarcomatous transformation. This article reports a case of facial plexiform neurofibromatosis with mandibular hypoplasia and reviews various oral soft tissue and hard tissue manifestations of neurofibromatosis I.

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