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Neuronal structure and need for improved action potential propagation modeling

Author: 
Suman Bhatia
Subject Area: 
Physical Sciences and Engineering
Abstract: 

The nervous system is made up of a large number of interacting neurons or nerve cells. Neuron is an electrically excitable cell that processes and transmits information through electrical and chemical signals. A typical neuron possesses a cell body or (soma), dendrites, and an axon. In neurons, action potentials play a central role in cell-to-cell communication. Once an action potential is initiated at one point in the nerve cell, it propagates through the axon to the synaptic terminal region and from there signal is transmitted to next neuron. Propagation and generation of action potentials have so far been studies by treating the whole system as consisting of electric circuit having conductance and resistances. However (from cell biology) we know that lot more is happening while action potential is being propagated through axon. Additionally with the advent of computers, now, we can afford to undertake more complicated modelling and analysis of action potential propagation. This will lead to improved understanding and better ability to improve neuronal performance. We therefore propose the possibility of modeling action potential propagation using Fluid equations and Maxwell equations.

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