Unicystic ameloblastoma is a rare, benign tumor of odontogenic epithelium. It refers to those cystic lesions that show clinical, radiographic and gross features of a mandibular cyst but on histological examination show a typical ameloblastomatous epithelium lining the cyst cavity with or without luminal and/or mural tumor growth. Most of the cases are associated with tooth impaction, the mandibular third molar being most often involved. This is the dentigerous variant. Sometimes, UA can occur in the ramus area without a relationship with teeth, the so-called ‘Nondentigerous’type. As per the literature, both the dentigerous and non dentigerous variant usually demonstrates unilocular radiolucency, although multilocular features also occur. Hence, it is essential that further studies should be conducted on a large scale in order to know whether both variants i.e. dentigerous and non dentigerous with unilocular and multilocular features can alter the prognosis and treatment plan of the lesion. We present a case of unicystic ameloblastoma – Nondentigerous type in a 38 year old patient showing multilocular radiolucency.