
Introduction: Cutaneous Warts are viral infection caused by human papilloma virus (HPV). In multiple warts or recalcitrant warts most of the destructive methods are painful therefore it is inappropriate. Materials and Methods: All patients clinically diagnosed as having multiple or recalcitrant warts were included in the study. Digital photographs were taken and all data recorded in the predesigned proforma. Results: There were total of 50 patients. Commonest age group of presentation was seen between 15 and 25years (should be deleted). Commonest age group of presentation was seen between 15 and 25years, 27(53%) patients, mean years of presentation was 36 years. Females were 60%. Commonest site of lesions was seen over face in 32%. 10 to 20 lesions were seen in 36% and more than 40 in 6%.Most common morphology of lesions were papules in 38%. In three month follow-up mild (25%) improvement was seen in 8%, moderate (50%) improvement in 34%, good (75% )improvement in 28% and excellent (100 %) improvement in 3(6%). Mild gastrointestinal side effects were seen in 4%.Drop out rate was 8%. Conclusion: Oral Zinc sulphate is a novel therapeutic option for treatment of multiple and recalcitrant wart with fewer side effects compared to other surgical modality.