Ozone is acquiring its place in the field of dentistry and in day to day dental practice. Since many years, it has been used owing to its oxidizing property, which makes it an excellent antimicrobial agent. Because of its potent anti-inflammatory property, favorable cellular and hormonal immune response, ozone acts as an effective therapeutic agent. Versatility of ozone therapy, its unique properties, non-invasive nature, absence of any side effects or adverse reactions were responsible for its wide spread use. Ozone’s potentiality of arresting and reversing carious lesions in a predictable way has led to a new chapter in minimal invasive dentistry. It has a wide application in conservative dentistry and in endodontics which includes treatment of carious lesions, root caries, hypersensitivity, disinfection of the root canal, bleaching, etc., without any toxic effects. It is important to look ozone as a synergistic part of the dental treatment, bacterial elimination and site of oxygenation. This poster summarizes the ability of ozone in treating various dental diseases and its possible clinical applications in future