In the present study, aqueous and ethanolic extracts of Curculigo orchioides was investigated for antimicrobial activity. The microorganisms employed were Erwinia amylovora, Klebsiella pneumonia, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa and Enterobacter cloacae. The susceptibility of bacterial strains against the two extracts were determined using the disk diffusion method. In the aqueous extract of C. orchioides showed maximum antimicrobial activity against Klebsiella pneumonia (18.49 mm) than other organisms. Proteus mirabilis shows minimum (6.34 mm) inhibitory activity against aqueous extract while Enterobacter cloacae have no inhibitory activity. Likewise, ethanolic extracts of C.orchioides rhizome exhibited maximum inhibitory activity against the all microorganism but differ in zone of inhibition (Klebsiella pneumonia – 27.3 mm) than other organisms. Among the two extracts ethanolic extract has maximum antimicrobial activity against the six microorganisms.
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