CALL FOR PAPERS

Author Information

CERTIFICATE

IMPACT FACTOR 2021

Subject Area

Life Sciences / Biology
Architecture / Building Management
Asian Studies
Business & Management
Chemistry
Computer Science
Economics & Finance
Engineering / Acoustics
Environmental Science
Agricultural Sciences
Pharmaceutical Sciences
General Sciences
Materials Science
Mathematics
Medicine
Nanotechnology & Nanoscience
Nonlinear Science
Chaos & Dynamical Systems
Physics
Social Sciences & Humanities

Why Us? >>

Open Access
Peer Reviewed
Rapid Publication
Life time hosting
Free promotion service
Free indexing service
More citations
Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

A potent plant compound from mangifera indica to treat diabetes

Author:

Chitra, P.

Subject Area:

Life Sciences

Abstract:

Type 1.5 diabetes also known as latent autoimmune diabetes in adults (LADA) is an important form of diabetes which occurs in about 10% of patients classified as type 2 diabetes and not initially requiring insulin. β- cell dysfunction in type 1.5 diabetes is caused mainly by Glutamic acid decarboxylase antibody (GADA). β- cell stress results in an induction of Heat shock protein 90 (Hsp90) expression, where Hsp 90 is a regulator of Class II antigen processing and presentation. In silico docking studies and drug likeliness analysis have shown that docking target protein Hsp 90 α with the ligand mangiferin had a protective role against autoimmune destruction. This study paves way for treating the autoimmune diabetes at the immunity level.

PDF file: