Effect of flaxseeds supplementation on serum lipid profile of hypercholesteromia induced animals was studied. Flaxseeds were processed (roasted), grinded and administered at dose of 250grams and 500 grams as low dose and high dose. Administration of roasted Flaxseed powder of 250 gm (low dose) and 500 grams (high dose) for 42 days produces significant (P<0.001) reduction of serum LDL-cholesterol and in body weight reduction in hyperlipidemia induced rats. The present study confirmed that roasted Flaxseeds powder incorporated would be considered as effective agent for lipid lowering purposes.