Aloe vera is the oldest medicinal plant ever known and the most applied medicinal plant worldwide. The plant leaves contains numerous vitamins, minerals, enzymes, amino acids and other bioactive compounds with emollient, purgative, antimicrobial, anti inflammatory, anti-oxidant, aphrodisiac, anti-helmenthic, antifungal, antiseptic and cosmetic properties. Aloe vera has been used in dentistry for its wound-healing effects, gingivitis, plaque control & curing oral mucosal lesions. Aloe vera may also reduces pain and duration of oral ulcers by rapid healing. The dentists should use Aloe vera to maximize its therapeutic benefit.