CALL FOR PAPERS

CERTIFICATE

IMPACT FACTOR 2019

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

 

 

 

 

 

 

 

 

 

 

 

Screening of in vitro antifungal activity of some indian medicinal plants against candida albicans and cryptococcus neoformans

Author: 
Sreerangegowda Thippeswamy, Devihalli Chikkaiah Mohana and Kiragandur Manjunath
Subject Area: 
Life Sciences
Abstract: 

The present investigation evaluates the anti-Candida albicans and anti-Cryptococcus neoformans activity of different extracts of thirty plants belonging to 16 families. Standard agar disc diffusion method was employed for determination of antifungal activity and standard two fold broth dilution methods was used for determination of the minimal inhibitory concentration (MIC) and the minimal fungicidal concentration (MFC). The test strain Cryptococcus neoformans used in the present study exhibited complete resistance to antifungal drugs clotrimazole and itriconozole. The result of the present study revealed that extracts of Acacia catechu, Acacia ferruginea, Adenanthera pavonia, Albizia amara, Caesalpinia coriaria, Decalepis hamiltonii, Holoptelea integrifolia, Prosopis juliflora, Samanea saman and Solanum indicum showed promising antifungal activity. The best antifungal activity was observed in toluene extract of A. pavonia and C. coriaria, chloroform extract of A. amara and methanol extract of P. juliflora and S. saman with zone of inhibition ranging from 9.2mm to 18.9mm against C. albicans and 10.5mm to 24.5mm against C. neoformans at 1mg/disc. The MIC and MFC values ranging from 0.125mg/ml to 0.5mg/ml and 1mg/ml to >2mg/ml against C. albicans and 0.0312mg/ml to 0.25mg/ml and 0.5mg/ml to 2mg/ml against C. neoformans respectively. The subsequent fractionation and phytochemical analysis confirmed that alkaloid fraction of A. amara, P. juliflora and S. saman and steroid fraction of A. pavonia and C. coriaria responsible for antifungal activity. Further investigations are required to identify active compounds responsible for activity and toxicological study using animal models before clinical application.

PDF file: 

IJMCE RECOMMENDATION

ONLINE PAYPAL PAYMENT

CURRENT ISSUE

NEWS

CHIEF EDITOR
Rosane Cavalcante Fragoso, Brasil
ASSOCIATE CHIEF EDITOR

   

Jean-Marc SABATIER
Chief Scientific Officer and Head of a Research Group
France

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

 

 

 

 

 

 

 

 

 

 

 

EDITORIAL BOARD

Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran