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The serum levels of malondialdehyde, cholesterol and total lipids in patients diagnosed as having typhoid salmonellosis in nsukka urban area, southeast Nigeria

Author:

Ihechiluru I. Ezeigbo and Chinaka O. Nwaehujor

Subject Area:

Health Sciences

Abstract:

The sera of clinically confirmed typhoid patients in Nsukka urban area, along with healthy individuals were collected and analysed for MDA, total cholesterol and total lipid levels. Results showed total cholesterol levels in typhoid patients as 142.22± 29.83 and of healthy individuals as 211.19±22.02. It also showed total lipid levels as 128.98±3.39 and 154.95±11.40 in typhoid and healthy individuals respectively. Mean MDA levels were observed as 1.073±0.51 and 0.820±0.53 in typhoid and healthy individuals respectively.The results show that inflammation of the bowel caused by Salmonella typhi infection may lead to oxidative stress-mediated production of reactive oxygen species, causing lipid peroxidation in typhoid patients.

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