A fingerprint is an impression left by the friction ridges of a human finger. Fingerprint patterns are unique in each individual. Since the beginning of twentieth century, fingerprint detection and analysis are being commonly used. It has become an important part of forensic investigation in crime scene. Therefore, it has got a great application in the court of law. Out of many blood grouping systems available, ABO and Rh systems are the most important and are considered for the present study. Aim of this study is to correlate the fingerprint patterns with gender and blood group of individuals. This prospective study was carried out in a time period of 2 months among 300 medical students (150 male and150 female) of Yenepoya Medical College, Mangalore. The fingerprint patterns are classified under loops, whorls and arches. Results show that loops are the most commonly found pattern followed by whorls and arches. Loops are predominant in females whereas whorls and arches are seen more in males. Highest frequency of loops was seen in O positive blood group.