CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Study on klebsiella pneumoniae carbapenemase and metallo beta lactamase enzymes in clinical isolates of gram negative bacilli

Author: 
Dr. Archana Bhat, K. and Dr. Nagarathnamma, T.
Subject Area: 
Health Sciences
Abstract: 

Background: Resistance to broad spectrum β-lactams mediated by Extended spectrum β-lactamases and AmpC β lactamases is an increasing problem worldwide. The advent of carbapenems heralded a new treatment option for serious bacterial infection. But carbapenemases have emerged and spread, leading to carbapenem resistance .Hence, it is necessary to know their incidence in the clinical isolates of the hospital, so as to formulate a policy of empirical therapy in high risk patients. Materials and methods: A total of 250 isolates of Gram negative bacilli isolated from various clinical samples received in the Department of Microbiology, BMC & RI were included in the study. Antibiotic susceptibility was done according to Kirby-Bauer disk diffusion method on Mueller Hinton agar and results were interpreted according to CLSI guidelines. Carbapenemases were screened and confirmed by CLSI recommended Modified Hodge test(MHT) and Phenyl boronic acid/Ethylene diamine tetra acetic acid (BA/EDTA) disk potentiation test. Results: The most common organism isolated was Escherichia coli (44%) followed by Klebsiella pneumoniae (29.6%). 3.2%, 12.8% and 3.6% were pure KPC, pure MBL and co-producer of KPC and MBL respectively. The BA/ EDTA disk potentiation test is better than MHT for detection of carbapenemase and MBL. Interpretation and Conclusion: The BA/ EDTA disk potentiation test is better than MHT for detection of carbapenemases and MBL and is a satisfactory and inexpensive method for characterizing the type of carbapenemase when PCR is not readily available. Thus the combined disc potentiation test could be used as a convenient screening method for carbapenemases.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran