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A study of serum lipid profile and oxidative stress marker in healthy pregnancy and in preeclampsia

Author: 
Lakshmiprabha, S., Biswajit Mohanty, Pradipta Kumar Mohanty, Diwakar, A., Dhanyasi Anil Kumar, Viyatprajna Acharya and Suganthy, K.
Subject Area: 
Health Sciences
Abstract: 

Objective: In India Pre eclampsia contributes to 15.2% maternal mortality. The present study was undertaken to compare the changes in lipid profile and oxidative stress marker (MDA) in normal pregnancy and in preeclampsia. Methods: A case control study was done on 26 PIH patients and 24 healthy controls. Serum Total Cholesterol, Triglycerides, HDLc, LDLc, VLDLc, Urinary proteins and Malondialdehyde (MDA) were estimated. Maternal Blood pressures were recorded. Results: Serum total cholesterol, triglycerides, LDLc, VLDLc were elevated. HDLc was decreased.MDA was thrice that of the controls. Conclusion: This study indicates that, dyslipidemia and oxidative stress leading to endothelial damage can contribute to cardiovascular risk in future in pre eclamptic women.

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