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Treatment of gout from nutritional values & different plant extracted compounds

Author: 
Nazish Waris, Rana Kausar and Mariam Rafique
Subject Area: 
Life Sciences
Abstract: 

Gout was treated by bottle gourd and Ficus Palmata specie. 24 rats were divided into 4 groups: control, model, bottle gourd treated and Ficus Palmata treated. Gout is induced by direct oral dose of uric acid as 30mg/kg body weight. Bottle gourd and Ficus Palmata extracts were prepared in ethanol separately and given to rats as 80mg/kg body weight. After 6 weeks of treatment behavioral activities were monitored. After decapitation, biochemical tests were determined by calcium, magnesium, phosphorus and serum uric acid. Locomotor and stimulator activities significantly increases in bottle gourd and Ficus Palmata treated group, anxiety decreases while, recognition memory of both groups significantly increases as compare to model but decreases as compare to control. Bottle gourd and Ficus Palmata rats showed good effects to enhance magnesium level in blood, significantly reduces the serum uric acid level and maintained calcium phosphorus balance in blood. P-value <0.05 was statistically significant.

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