The annual world production of wheat is approximately 758 million tons. In Côte d'Ivoire, the quantity of wheat imported is more than 550 000 tons. Wheat thus occupies an important place in the Ivorian diet. However, its cultivation is struggling to take off in the country because of climatic conditions unfavorable to its productivity. A study was initiated with the main objective of evaluating the agronomic characteristics of five wheat accessions and their resilience to climate change in west-central Côte d'Ivoire. Five wheat accessions, including three from Morocco obtained in Marrakech (AM), Tanger (AT) and Safi (AS); two from Nigeria (AN) and Côte d'Ivoire (AC). A completely randomized design was used with pots. Three treatments (T0, T1, T2) were applied to the 5 different accessions. The seedlings were sown on the same day in 5 dm3 pots, filled with a substrate composed of soil and chicken droppings. The control pot (T0) was filled with 100% soil. T1 is filled with 20% chicken droppings for 80% soil. T2 was filled with 40% chicken droppings and 60% soil. The different organic manures of treatments T1 and T2 significantly increased the vegetative and production parameters of wheat. The effect of different treatments on grain production of wheat accessions showed significant difference with T2 treatment. Accession Nigeria had the highest number of spikes per plant (5.4) and spikelets per spike (27.5). It had the highest number of grains per spike (19.0). The highest grain filling rate (74.6%) of wheat was also observed with the same accession Nigeria for the same treatment T2. The effect of different treatments on grain production of wheat accessions was very highly significant (p<0.001). Of the five accessions evaluated (AM, AT, AS, AN and AC), only the AN accession was the most productive.