The main aim of the present study was to validate the nutritive value of economically important fish Schizothorax plagiostomus of Kashmir valley. Schizothorax plagiostomus (Khont) Heckel, 1838, locally available teleost of Kashmir valley were sampled form March 2012 to February 2013 to analyze the seasonal and monthly variation in the total protein content of muscle tissue. Results show that the nutritive value of a species of fish varies throughout the year. Marked fluctuations in protein content of the fish have been analyzed during the study period. Highest protein values in muscles of Schizothorax plagiostomus were recorded in July and lowest was observed in the December. In conclusion, it was seen that protein content in the muscle of Schizothorax plagiostomus was significantly influenced by the season, spawning, availability of food etc.