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Relationship between antioxidant supplementation and progression of age related macular degeneration

Author: 
Fayez Alshehri, Mohammed Alshehri, Mohammed Almashiakhi and Ibrahim Elmenshawi
Subject Area: 
Health Sciences
Abstract: 

Background: Age related macular degeneration is the leading cause of visual loss in western population in patients older than 60 years old. As Oxidative stress has been implicated in the etiology of age related macular degeneration, antioxidant supplementation could be of benefit to prevent or slow the progression of this disabling disease. Objectives: The aim of this review is to investigate the relationship between antioxidant supplementation and the progression of age related macular degeneration. Methods: A literature search using Medline database was conducted for the years 1946 to 2017 to explore the relationship between antioxidant supplementation and the progression of age related macular degeneration. The search was restricted to studies published in English language. The first 30 articles were reviewed and five relevant studies were selected in this analysis. Results: Impacts of antioxidants supplementation on progression of age related macular degenerationwere investigated in five studies. Dietary intake of antioxidant supplementation was associated with slow progression of age related macular degeneration, improve vision, and reduce risk of developing age related macular degeneration in elderly people. Conclusion: Antioxidants supplementationcould slow the progression of age related macular degeneration. Furthermore, supplementation of antioxidants might improve the visual function in patients with age related macular degeneration.

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