Aim: To evaluate the adjunctive effect of Triphala gel with scaling and root planing in the treatment of chronic periodontitis. Materials and Methods: Subjects diagnosed with localized or generalized chronic periodontitis with pocket depth ≥4mm were selected for study. Two non-adjacent sites in different quadrants of the mouth were randomly divided into control sites and experimental sites.30 control sites were treated by SRP alone, and 30 experimental sites were treated with SRP followed by placement of 6% Triphala Gel in the periodontal pocket. Following parameters will be recorded at baseline and after 30 days: Plaque index (Turesky- Gilmore- Glikman modification of Quigley Hein plaque index) Gingival index. Sulcus bleeding index Pocket probing depth Clinical attachment level. Trypsin-like activity of “red complex” microorganisms by BAPNA assay Results: The test group exhibited a significantly lower mean score for the recorded parameters as compared to the control group. The difference between two groups was statistically significant. Conclusion: The experimental local drug-delivery system containing 6% triphala can be effectively used as an adjunct to scaling and root planing and is more effective than scaling and root planing alone in the treatment of periodontal pockets.