Mucormycosis is a life threatening illness, encountered lately as a sequel of post COVID 19 infection which is commonly found in immunocompromised individuals especially with diabetes mellitus. Due to the aggressive disease progression if not diagnosed early and treated appropriately with antifungals and surgical debridement, the mortality rate rises remarkably. Anaesthetists face challenges in view of poor general condition, hemodynamic instability and difficult airway of the patients. In this case ketamine was used as inducing agent along with propofol and was also used as maintenance agent demonstrating the usefulness and efficacy of the drug.