
Adhesion is a phenomenon of general significance that governs the evolution of microorganisms and their interaction in all the environments in which they occur, that is to say in the whole of the biosphere. The elucidation of the mechanisms at the molecular level of bacterial adhesion to solid surfaces has not been fully accomplished. The oral cavity is part of these environments, the bacterial adhesion is interested in different structures in the mouth: dental structures, mucosal structures and structures of therapeutic interest (composite, brackets, orthodontic wire, ceramic, titanium…). The adhesion phenomenon involves nonspecific factors of different types (ionic, dipolar, hydrophobic, hydrogen bonding) between the macromolecules on the surface of the microorganisms and those of the support and other specific factors. Stereochemical order involves interactive complementary chemical groups. Our study is used to observe the behavior of bacteria in contact with tooth surfaces and titanium, in order to understand the adhesion mechanism. The aim of this work is to study in vitro the behavior of certain bacteria of the oral flora in contact with a dental surface and titanium to: • Observe the ability of these germs to adhere to tooth surfaces and titanium. • Evaluate quantitatively the adhesion and proliferation potential of these germs in contact with tooth surfaces and titanium. • Compare their behavior in contact with these 2 surfaces. The results of our work have shown that the three germs used have different behaviors and even adhesion capacity on the two surfaces. In contact with the tooth surfaces the three seeds were able to adhere and proliferate, in contrast in contact with the titanium surfaces, an inhibition of this adhesion was observed. Germs need more time in contact with surfaces to adhere and proliferate. The results showed the importance of surface characteristics and more precisely the influence of surface roughness on the adhesion of bacteria.