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A clinical study to evaluate the efficacy of Ayurvedic formulations in the management of Kamala w.s.r. to Impaired Liver Function

Author: 
Dr. Uma Thakur and Prof. Mehra, B.L.
Subject Area: 
Health Sciences
Abstract: 

Introduction: Kamala is one of the important common clinical entity in Ayurveda whose description appears to be most comprehensive and incorporates the disorders of hepatobiliary system of modern medicine. In Ayurvedic literature Kamala has been mentioned as a sequel of Pandu roga. It occurs when Pandu rogi takes more Paittikaharavihara1. Jaundice, a yellowish discoloration of tissue resulting from the deposition of bilirubin is the common presentation of patients with liver and biliary diseases. The liver diseases have remained a challenge to medical profession since many of the liver disorders may ultimately lead to irreversible changes. Liver function tests along with liver enzymes constitutes group of tests used to determine the state of liver function in a patient. Materials and methods: Literary material from Ayurvedic and Modern texts was compiled and assessment criteria was formulated.15 patients of age 10-70yrs were registered from OPD/IPD of R.G.G.P.G.A.C Paprola fulfilling the inclusion criteria. Drug, Dosage and Duration: One group of minimum 15 patients were treated with both the trial drugs i.e. Trivritchuran with Sharkara 4gm orally twice a day for 7 days and Kamalaharyoga- Liver tone syrup 10 ml TID for 30 days and Liver tone capsule 1 BD for next 30 days . Duration of trial was 60 days with follow up after every 15 days. Observations Effect of therapy on Subjective and Objective Parameters: Out of those 13 patients who completed the study;38.46% patients were completely relieved, 3 patients each with the percentage of 23.07% reported mild and moderate improvement, marked improvement in patients symptoms and biochemical improvement was found in 7.70% of patient and 7.70% reported no relief in symptoms and signs of disease Results and conclusion: Therapy has significant role in relieving symptoms and signs of the disease. It showed better efficacy on subjective criteria than biochemical criteria. No adverse effects were observed during the course of trial.

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